In 1945, Hoover, realizing that there were limits to what the Bureau could accomplish, revived the centuries-old Millennium Group and attempted to persuade Michael Lanyard to join them. (MM: "Matryoshka")
In 1946, Hoover initiated the first "unsolved file," later known as an X-File, based on the death of Richard Watkins, who had transmuted from a wild animal. Hoover found the case too bizarre to be solved adequately and hoped that by labeling it unsolved, it would be forgotten. (TXF: "Shapes")
In 1968, Hoover's attempts to stop Martin Luther King, Jr. from spreading communism by sending him a letter urging suicide failed, and he was forced to use more drastic measures, by sending the Cigarette Smoking Man after him. (TXF: "Musings of a Cigarette-Smoking Man")
- The events of 1968 were written in the semi-fictional novel Take a Chance: A Jack Colquitt Adventure by the Cigarette Smoking Man under the alias of Raul Bloodworth, and may or may not have actually occurred.
In 2008, a photograph of Hoover could be seen inside FBI Headquarters in Washington, D.C., on the right of a door to a conference room in the building. A photograph of President George W. Bush could be seen on the left of the same door. (The X-Files: I Want to Believe)